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Diffuse Large B-Cell Lymphoma Alternative Therapy

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Diffuse Large B-Cell Lymphoma Alternative Therapy

Diffuse large B-cell lymphoma (DLBCL) is the most prevalent form of non-Hodgkin’s lymphoma (NHL), accounting for 30% to 35% of all NHL cases in America.

Treatment options for diffuse large B-cell lymphoma have significantly improved over the last four decades due to improved definitions of the disease, improved diagnostic capabilities, enhanced staging and restaging techniques, a useful prognostic index to guide therapeutic decisions, and increasingly effective therapies.

The most commonly prescribed treatment for diffuse large B-cell lymphoma is rituximab and anthracycline-based multiagent chemotherapy, which has resulted in cures in approximately half of patients with this type of lymphoma.

Non-Hodgkin’s lymphomas include angioimmunoblastic T-cell lymphoma and extranodal natural killer/T-cell lymphomas, which affect the lungs, skin and paranasal sinuses (hollow spaces around the nose). Another form is systemic anaplastic large cell lymphoma which starts in lymph nodes.

Immunotherapy is a type of treatment that utilizes medications to attack cancer cells and other cells in your body, either alone or combined with chemotherapy or radiation therapy.

Some people with diffuse large b-cell lymphoma receive high doses of chemotherapy to target and eliminate rapidly growing lymphoma cells. This may be followed by a stem cell or bone marrow transplant to replace damaged lymphoma cells with healthy ones.

Chemotherapy is a type of treatment that uses either IV or oral administration of medicine to kill cancer cells. This therapy usually includes radiation therapy and/or targeted immunotherapy drugs like rituximab.

Intrathecal chemotherapy (R-CHOP) is an effective treatment for lymphoma that has spread to your brain and spinal cord. This approach involves injecting a chemotherapy drug into the fluid surrounding your spinal cord in cycles, usually combined with the immunotherapy drug rituximab – known as R-CHOP – which has become one of my go-to treatments when dealing with this type of lymphoma.

Traditional chemotherapy does not cause serious side effects, making it a viable treatment option for patients with diffuse large b-cell lymphoma who don’t have an immune system strong enough to fight off infection from cancer cells that might escape the bloodstream.

To determine if you are eligible for this treatment, your doctor should perform a complete blood count and physical exam. If necessary, an imaging test will be done to check for lymphoma growth within organs.

Additionally, you will be given a positron emission tomography scan and other tests that check for changes in your lymph nodes or other areas of your body. These measures can help determine how rapidly lymphoma is growing and where it may spread.

Your doctor may ask if you would like to participate in a research trial, which is an investigation of different treatments for an illness. Through research, doctors and scientists learn how to make existing treatments more effective and create new ones. This can be an excellent opportunity for getting better treatments that will be more beneficial to you.

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