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Ketamine Infusion Therapy For Chronic Pain

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Ketamine Infusion Therapy For Chronic Pain

Ketamine infusion therapy for chronic pain has been demonstrated to provide significant analgesic relief when compared with placebo in multiple clinical studies. It may be an effective treatment option for those suffering from neuropathic pain, complex regional pain syndrome (CRPS), and postherpetic neuralgia.

Ketamine infusions for pain have a powerful analgesic effect due to their capacity to anesthetize or inhibit N-Methyl-D-Aspartate (NMDA) receptors found throughout the central nervous system and peripheral axons that transmit pain signals. By blocking these receptors, ketamine reduces signals related to pain while increasing inflammation; additionally it blocks some sodium and potassium channels which increase levels of gamma-aminobutyric acid A (GABA) in the brain – another chemical which helps reduce discomfort and promote relaxation.

A recent meta-analysis involving 211 patients across seven studies demonstrated that intravenous ketamine infusions produced significant analgesic effects for both neuropathic and nonneuropathic pain conditions. The magnitude of pain reduction was significantly greater than placebo up to two weeks after the infusion, and effects persisted for several months.

Ketamine not only provides analgesia, but has been demonstrated to reduce microglial activation and neuronal inflammation in animal models of neuropathic pain. These anti-inflammatory and antioxidant effects are likely the major reason why ketamine may be so helpful for those suffering from neuropathic discomfort.

Ketamine also activates descending inhibitory pathways in the spinal cord and brain stem that suppress pain signals from the dorsal horn. This is an essential factor in chronifying pain signals and maintaining long-term pain control.

If you are thinking about trying ketamine infusion therapy for your chronic pain, it’s essential to speak with your healthcare team first about whether this type of treatment is right for you. Make sure they know about any other treatments you have tried, medications you are taking, and any underlying health issues which could contribute to the discomfort.

When seeking medical care for chronic pain, always opt for a center that has board-certified physicians on staff who have expertise in administering ketamine infusion therapy. Doing so will guarantee the highest quality care and the most successful results.

Ketamine infusion therapy for chronic pain often causes nausea, vomiting, sedation and low blood pressure. Since adverse events can happen at any time during or after your ketamine infusion therapy, it’s essential to communicate with your healthcare team if you experience any concerns.

Ketamine infusions for chronic pain can be administered via IV, injection or inhalation. Initially, ketamine is given at a low dose that may be increased over time; typically, one hour of continuous infusion will provide enough effect.

Ketamine used for infusion is often combined with a benzodiazepine to help mitigate its sedative and psychotropic side effects. While this combination can be successful in relieving anxiety and moods of some patients, it should be remembered that not everyone responds to ketamine infusion therapy.


- Welcome, this post an excerpt from our research that matches your search. Our site is a sound therapy service that lowers anxiety 86%, lowers insomnia, lowers pain 77%, lowers tinnitus 78%, helps memory 11-29%, and more (all are averages). It is free to try and share. You can repost this information on other networks with the buttons below:
SoundTherapy - for an average of 77% less anxiety, insomnia, and pain.