Most sedatives act selectively on specific neurotransmitters and neuromodulators in the CNS (Schwartz 2000). Benzodiazepines, Z drugs, atypical antipsychotics, and tricyclic antidepressants (except low-dose doxepin and nortriptyline) should be avoided in older adults, patients with untreated sleep apnoea, and patients with chronic nocturnal hypoxia. After taking an insomnia medicine, do not try to drive or do other activities that require concentration, as this will make you drowsy and may increase your risk of accidents. According to the NIH, most evidence supports the effectiveness of cognitive behavioral therapy and short-acting benzodiazepine receptor agonists in treating chronic insomnia, at least in the short term.
All medications can be considered first-line remedies for sleep disorders. Drug selection is largely determined by previous studies, costs, side effect profile, drug interactions, and patient preferences.
What is the drug of choice for sleep disorders?
Research suggests that Ramelteon has no potential for abuse and that the drug is not classified as a controlled substance. On average, people who take one of these drugs only sleep a little longer and better than people who don’t take any medication. And taking certain prescription sleeping pills can lead to substance abuse or addiction. Therefore, it is important to follow your doctor’s advice. These medications may increase the risk of falls, vehicle accidents, memory problems, and daytime sedation, particularly in older adults.